In this article, the compatibility of Populus davidiana, Betula plotyphylla, Quercus mongolica and Picea abies as well as the mixture of the former three species with the manufacture of gypsum-bonded particleboard was studied At same technical parameters, the gypsum-bonded partieleboard made of the lower density species with higher MOR, i. e. spruce board is the strongest, then poplar and birch, the board made of oak is the weakest. Spruce and poplar are suitable species for the manufacture of gypsum-bonded particle-board But the qualified birch and oak boards were not obtained even through the change of wood-gypsum ratio and wood particle Volume, water extraction of wood particle. Mixture of various wood species will not only offset the hydration time, but also make the quality of gypsum-bonded partieleboard unstable, which should be avoided in practice.