To explore potential applications of three-dimensional（3 D）printing technology in developing anti-compression/lightweight products with wood-plastic filaments,twelve infill patterns including six two-dimension and six three-dimension infill patterns were selected to prepare wood plastic composite specimens.The flatwise compression properties of the specimens were measured and analyzed.The two-dimension infill patterns presented high flatwise compression strength and modulus of compression.The three-dimension infill patterns were suitable for rapid prototyping in product design and manufacturing.The two-dimensional tri-hexagon infill pattern had good flatwise compression properties with high printing efficiency.