Based on life cycle assessment（LCA）, raw material consumption, energy consumption and environment emissions during production, 1 m,3, of oriented strand board（OSB） was analyzed using Gabi ts software. Results showed that acidification effect（AP）, photochemical ozone creation potential（POCP） and global warming（GWP 100） accounted for 52.1%, 23.7% and 20.8% of the total environmental impact. The main environmental influence factors of OSB production, blending, hot pressing and stranding accounted for 28.4%, 18.0% and 16.8%. The input of power and adhesives were key inventory data that had the greatest impact on AP, POCP and GWP 100.