Nano-MgO was used as a catalyst to prepare lignin-phenol-formaldehyde（LPF） resin which was composed of 50% enzymatic hydrolysis lignin.The effects of synthesis parameters were studied including:molar ratio of formaldehyde and phenol（F/P）, nano-MgO usage and molar ratio of sodium hydroxide to phenol（NaOH/P） on gel time and storage life of the LPF resin and bonding strength of plywood samples bonded with the LPF resin.The results indicated that optimum manufacturing technology were 1.9 molar ratio of F/P, 1.5% of nano-MgO usage and 0.9 molar ratio of Na OH/P.The gel time of the LPF could be shortened by 30%.The bonding strength of the plywood samples bonded with the LPF resin could meet National Standard GB/T 9846-2015 requirement for I-level plywood.