This paper investigates six kinds of selected preservatives as antifungal and anti-insect （agents） for wood flooring and other wood products and their application, such as the compound of boride and sodium pentachlorophenol, organophosphorus agent, quaternary ammonium salts and pyrethroids. To evaluate their resistance against Coriolus versicolor and termites, a series of experiments for Korean Pine （Pinus koraiensis） wood sample were carried out. By comparison between treated samples and controls, the results showed the mixture of quaternary ammonium salts and pyrethroids was the most effective but least harmful preservative, and was suitable for wood flooring and other indoor wood products. The results also established a base for developing a standard for this preservative treatment.