The house climate (including temperature and relative humidity of inside and outside of wall surface, the distribution in vertical space of temperature and relative humidity inside, etc.) of oriented structural board (OSB) building and brick building in winter and summer were tested by automatic recorder. It was indicated that the house climate of OSB building (the structure of wall is OSB+glass wool+OSB) was better than that of the brick and concrete building for human’s health. The indoor temperature of OSB building is steady.